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Hyperhidrosis Medication

Systemic medication can be utilized for the medication and cure of generalized or focal hyperhidrosis. A lot of the medicines said to be helpful in treating hyperhidrosis have not been thoroughly tested in controlled laboratory experiments. Their utilization and effectiveness are only being based on subjective proof and hearsay. Moreover, at the dosage needed to inhibit hyperhidrosis effectively, it is most likely that the side effects of such substances can be debilitating to the patient. On top of that, most of these medicines are not even accepted by the United States Food and Drug Administration (USFDA) as treatment for the cure of hyperhidrosis disorder.

The most frequently used or abused drug medication for hyperhidrosis treatment is anticholinergic drugs. This particular drug obstructs the sympathetic stimulus of the eccrine glands by restraining the activity of acetylcholine at the synapse. The applications of these particular drugs are limited and restricted. The common side effects that are generally found and associated from the anticholinergic class medication may comprise of constipation, dry mouth, urinary retention, and visual disturbances such as mydriasis and cycloplegia.

Anticholinergic drugs utilized for the treatment of hyperhidrosis include such drugs as benztropine, glycopyrronium bromide, oxybutynin and propantheline. When stressful circumstances are expected to set off hyperhidrosis, the use of anticholinergic agent or benzodiazepine before the onset will most probably be beneficial. The drug acts as a preventive measure that stops the onset of extreme perspiration brought about by anxiety or stress.

The long-term utilization and application of benzodiazepine drugs such as diazepam is restricted due to the possible drug dependence of the patient. A lot of patients have also been noted to be lacking in tolerance to the sedative effects of such medication. A number of patients take five milligrams of diazepam before sleeping at night. They do this for several weeks to get used to its sedating effect. When the need arises during stressful situations they can then take the necessary meds without fear of its effects and/or side effects.

There have been numerous unverified accounts of people with hyperhidrosis responding to varied methods of systematic medication. Most of these accounts are single cases and there are also a small number of patients with specific types of hyperhidrosis responding to a variety of systemic medication. Such medications utilized include the following:

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Hyperhidrosis Treatment

Treatment choices that are offered to people suffering from primary hyperhidrosis can be classified into two treatments: Non-surgical (topical antiperspirants, iontophoresis, systemic medication) treatment and surgical (endoscopic thoracic sympathectomy, excision of axillary tissue) treatment.

Botulinum toxin injection is supposed to be minimally invasive and has become an accepted therapy for patients who do not react favorably to more conventional forms of treatment.  This treatment therapy is normally done prior to resorting to surgery. Different therapeutic alternatives also vary in their length of efficacy. Side effects and response speed differ depending on the anatomic area treated. Topical therapy for focal hyperhidrosis or generally called antiperspirant treatment can be carried out with chemicals of several different classes. These classes comprise of astringent agents, topical anticholinergics, local anesthetics, and aluminum and other metallic salt solutions.

Most of the population in developed countries uses easily available over the counter antiperspirants for cosmetic and hygienic control of underarm sweating and odor. Individuals suffering from moderate to severe hyperhidrosis on the other hand require stronger remedies. Prescription medication and specially compounded solutions are commonly required for hyperhidrosis sufferers. Unfortunately these cures do not always give the desired effect.

Various topical agents analyzed are not easily obtainable commercially or do not have United States Food and Drug Administration endorsement and approval for the cure of hyperhidrosis. Only aluminum chloride has the approval of the USFDA for hyperhidrosis treatment. The preliminary treatment usually made for hyperhidrosis is normally non-invasive and does not necessitate any surgical procedure. There are commercially available ointments and salves (i.e., Drysol) that work as astringents and they have a tendency to dry up the sweat glands.

On the other hand, a different and acceptable cure for hyperhidrosis is iontopheresis. This is a hyperhidrosis treatment wherein electrical stimulation is used to lessen sweating. This procedure is normally done on the hands. Patients put their hands in a bath or basin of water wherein an electrical current is passed. This procedure stuns the sweat glands and tends to decrease the secretion of sweat for periods ranging from six hours to about 7 days.

One of the latest cures offered for hyperhidrosis is the injection of botulinum toxin or more commonly known as Botox. It is injected into the area where excessive sweating is experienced. This is a toxin that affects and sort of paralyzes the nerve endings. This toxin eventually reduces the transmission of the nerve impulses to the sweat glands which in turn results to reduce perspiration. It would normally require quite a few injections in the palms of the hands or armpits to complete the procedure.  The effect of the procedure is observed to range from 1 month to 6 months. Continual injections are practically needed to sustain an acceptable level of dryness.

Besides the above-mentioned treatments, many drugs and remedies have been used with varying degrees of success. These include sedatives (for patients with stress induced hyperhidrosis) and medications that have an effect on our central nervous system. A family practitioner or internist is usually the one who makes the diagnosis and initial treatment for hyperhidrosis. Hyperhidrosiscases that do not respond accordingly to simple treatment regimens are often referred to a specialist such as a dermatologist or neurologist. As a rule of thumb, surgery is only considered when the less invasive medical treatments have been exhausted.

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